She wanted to be a nun
Frances (Francesca) Busso was born into an aristocratic family in Trastevere, Rome, in 1384. Her mother was quiet-mannered and religious, her father strong willed. At eleven Frances wanted to become a nun, but her father arranged a marriage with aristocrat Lorenzo dei Ponziani. This caused her great pain but she came to have a loving relationship with Lorenzo. they lived in the same palazzo as her parents-in-law. Frances's mother-in-law Cecilia was totally taken up with organising parties and banquets  Frances, on the other hand, was more attracted to prayer and fasting. However, she found a companion and ally in her sister-in-law Vanozza who lived with her husband in the same palazzo. She had also wanted to be a nun. Both found a way to be cheerful amid their obligations to the family, and also to find time together for devout practices and works of charity.
 
Mistress of the household
Frances had two boys Battista and Evangelista and a daughter Agnes. When Cecilia died, it was she who became the mistress of the household, a job she accomplished with skill and fairness to all. Generous-hearted, she would give away corn and wine to the poor during the famine and though the granary and wine cellar often became empty, they were just as often miraculously replenished, to the dismay of her father-in-law and her husband.

When Ladislaus of Naples invaded Rome and took off John XXIII (then one of three antipopes) as a prisoner, Lorenzo who was commander of the papal troops was seriously wounded and their son Battista taken hostage to Naples. The plague then struck Rome and Evangelista died. Frances turned their palazzo into a hospital and shelter for the homeless.

A special guardian angel
One year after his death Evangelista came to his mother in a vision and told her that Agnes was going to die too. In return God was sending a special angel to be her guardian, companion and spiritual adviser. (This angel appears along with the statue of St Frances in the Basilica of St Peter's in Rome).

After the war Lorenzo and Battista returned home. Lorenzo was broken in mind and body. Much of Frances's time and attention was given to nursing him back to his old self.

Her own daughter-in-law
When Battista by now had grown into a charming young man. He married a pretty young woman named Mabilia. Frances expected Mabilia would share in the management of the household. But Mabilia only wanted to party. She would ridicule Frances in public for her shabby green dress, her habits, and her standards. But one day in the middle of yelling at her, Mabilia suddenly turned pale and fainted, crying, "Oh my pride, my dreadful pride." Frances had to nurse her also back to health and the differences between them were healed as well. A converted Mabilia did her best to imitate Frances after that.

The Oblates of Mary
With Lorenzo's support and respect, Frances started a lay order of women attached to the Benedictines called the Oblates of Mary. The women lived in the world but pledged to offer themselves to God and serve the poor. Eventually they bought a house where the widowed members could live in community.

Frances nursed Lorenzo until he died. His last words to her were: "I feel as if my whole life has been one beautiful dream of purest happiness. God has given me so much in your love."

After his death, Frances moved into the house with the other Oblates and was their superior for the four remaining years of her life. She now had the life she dreamed of when she was eleven. But God had had other things for her to do in between.

Her death and influence
Frances's last words were: "The angel has finished his task - he beckons me to follow him". She was buried in the Church of Santa Maria Nuova (now called Santa Francesca Romana), where her relics still rest. She was canonised by Pope Paul V in 1608. Possibly it was because she had such continuous contact with her guardian angel that Pius XI named her the patron saint of motorists.